Identifying Immunological Endotypes in Chronic Obstructive Pulmonary Disease (COPD) (Record no. 237094)

MARC details
000 -LEADER
fixed length control field 01257nam a2200121Ia 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 231221s9999 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Honey Sharma.
245 #0 - TITLE STATEMENT
Title Identifying Immunological Endotypes in Chronic Obstructive Pulmonary Disease (COPD)
Remainder of title Reshma Ashok.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2018-2019
Name of publisher, distributor, etc. PES University
Place of publication, distribution, etc. Bengaluru
510 ## - CITATION/REFERENCES NOTE
Name of source Chronic obstructive pulmonary disease (COPD) is obstruction of airflow in and from the lung. COPD is an autoimmune disease caused by the over expression or under expression of certain inflammatory cell and related proteins. In this study, we were trying to characterise COPD based on certain proteins produced, which can be utilised as endotypes for classification of the disease. The study helps us to correlate COPD to Th17 pathway, which is considered major effector pathway in the disease.ROR?t is a transcription factor involved in the programming of CD4+ T cells to the Th17 cell type. The cell type is determined by using antibodies against cell surface marker on fluorescence assorted cell sorter (FACS).Proteins are chosen based on the proximity level to ROR?t. The cytokines and chemokines is determined by two current techniques that is Luminex and single molecular counting SMC
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26/01/2024   CD7221 26/01/2024 Compact Disks       Central Library Central Library   BT/PG RS 1  

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