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Agent based simulation of DCIS [electronic resource : Project Report] Sanjay kumar G

By:

Bhargavi R Deepika Kumar Nandini R Smitha R K

Material type:

TextLanguage: English Series: NULLPublication details: PESIT, Dept. of BT, BangaloreSubject(s):

DDC classification:

PRBT07-1164

Summary: The objective of this project is to simulate the inception, development and treatment of a common cancer in women, namely, Ductal Carcinoma In Situ (DCIS) using agent based simulation methods. NetLogo, a freely available programming cum modeling environment for agent-based simulation is the platform used for developing the model of ductal carcinoma in situ (DCIS). The Two-Hit Hypothesis of cancer development has been used to simulate the inception of cancer. Cell cycle durations in normal and transformed cells have been taken into consideration while developing the model. The process of metastasis and effects of chemotherapy have also been simulated. The representative chemotherapeutic agent chosen is the nitrogen mustard alkylator, Cytoxan. The simulation closely mimics the general process of cancer growth and is an useful tool for pedagogic purposes.

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Holdings
Item type	Current library	Collection	Call number	Vol info	Status	Barcode
Project Reports	Central Library Central Library	Central Library	PRBT07-1164 (Browse shelf(Opens below))	(29/06/1905)	Available	PR1164

The objective of this project is to simulate the inception, development and treatment of a common cancer in women, namely, Ductal Carcinoma In Situ (DCIS) using agent based simulation methods. NetLogo, a freely available programming cum modeling environment for agent-based simulation is the platform used for developing the model of ductal carcinoma in situ (DCIS). The Two-Hit Hypothesis of cancer development has been used to simulate the inception of cancer. Cell cycle durations in normal and transformed cells have been taken into consideration while developing the model. The process of metastasis and effects of chemotherapy have also been simulated. The representative chemotherapeutic agent chosen is the nitrogen mustard alkylator, Cytoxan. The simulation closely mimics the general process of cancer growth and is an useful tool for pedagogic purposes.

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